I put this in a SitePoint Developer Survey I recently filled out:
"Domination of the desktop. Data will become more important to users than vendors. The Web will be come the "protocol" for the new desktop--both on-line and off. Standards will continue to be the road on which innovation travels. The sticky-wicket will be implementations of those standards. Open Source (hopefully) will rise to the occasion of implementing them--sometimes with company backing, sometimes without."